Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans
Identifieur interne : 001318 ( Main/Exploration ); précédent : 001317; suivant : 001319Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans
Auteurs : Julian W. Tang [République populaire de Chine] ; Karry L. K. Ngai [République populaire de Chine] ; Paul K. S. Chan [République populaire de Chine, Hong Kong]Source :
- Journal of Medical Virology [ 0146-6615 ] ; 2008-11.
Abstract
In a small pilot study, sera from 10 healthy human volunteers were taken pre‐vaccine, then 1, 3, and 6 months post‐seasonal influenza immunization (using the 2005/2006 Northern hemisphere vaccine: A/New Caledonia/20/99(H1N1)‐like, A/California/7/2004(H3N2)‐like, and B/Shanghai/361/2002‐like strains). Eight out of 10 subjects demonstrated satisfactory HAI titers (≥40) after seasonal influenza vaccination between 1 and 6 months post‐vaccine. These sera were then tested for inhibitory activity against A/HK/483/97 and A/Thailand/1(KAN‐1)/04 H5N1 influenza viruses using standard hemagglutination inhibition and microneutralization assays. In contrast to several other studies in both humans and animals on the cross‐immunity between different influenza A viruses, antibodies produced to the influenza A(H1N1) component of the seasonal influenza vaccine showed no cross‐reactivity to these avian influenza A(H5N1) viruses. Possible reasons for this contrasting result are discussed. J. Med. Virol. 80:1992–1996, 2008. © 2008 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/jmv.21321
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000569
- to stream Istex, to step Curation: 000569
- to stream Istex, to step Checkpoint: 000351
- to stream Main, to step Merge: 001331
- to stream Main, to step Curation: 001318
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans</title><author><name sortKey="Tang, Julian W" sort="Tang, Julian W" uniqKey="Tang J" first="Julian W." last="Tang">Julian W. Tang</name></author><author><name sortKey="Ngai, Karry L K" sort="Ngai, Karry L K" uniqKey="Ngai K" first="Karry L. K." last="Ngai">Karry L. K. Ngai</name></author><author><name sortKey="Chan, Paul K S" sort="Chan, Paul K S" uniqKey="Chan P" first="Paul K. S." last="Chan">Paul K. S. Chan</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:3AA3B59181D9E3A52D039146E92B16F2E0E94C9E</idno><date when="2008" year="2008">2008</date><idno type="doi">10.1002/jmv.21321</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-6HWJCQCL-R/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000569</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000569</idno><idno type="wicri:Area/Istex/Curation">000569</idno><idno type="wicri:Area/Istex/Checkpoint">000351</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000351</idno><idno type="wicri:doubleKey">0146-6615:2008:Tang J:lack:of:cross</idno><idno type="wicri:Area/Main/Merge">001331</idno><idno type="wicri:Area/Main/Curation">001318</idno><idno type="wicri:Area/Main/Exploration">001318</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans</title><author><name sortKey="Tang, Julian W" sort="Tang, Julian W" uniqKey="Tang J" first="Julian W." last="Tang">Julian W. Tang</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Ngai, Karry L K" sort="Ngai, Karry L K" uniqKey="Ngai K" first="Karry L. K." last="Ngai">Karry L. K. Ngai</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Chan, Paul K S" sort="Chan, Paul K S" uniqKey="Chan P" first="Paul K. S." last="Chan">Paul K. S. Chan</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Hong Kong</country></affiliation><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Correspondence address: Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Medical Virology</title><title level="j" type="alt">JOURNAL OF MEDICAL VIROLOGY</title><idno type="ISSN">0146-6615</idno><idno type="eISSN">1096-9071</idno><imprint><biblScope unit="vol">80</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="1992">1992</biblScope><biblScope unit="page" to="1996">1996</biblScope><biblScope unit="page-count">5</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2008-11">2008-11</date></imprint><idno type="ISSN">0146-6615</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0146-6615</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In a small pilot study, sera from 10 healthy human volunteers were taken pre‐vaccine, then 1, 3, and 6 months post‐seasonal influenza immunization (using the 2005/2006 Northern hemisphere vaccine: A/New Caledonia/20/99(H1N1)‐like, A/California/7/2004(H3N2)‐like, and B/Shanghai/361/2002‐like strains). Eight out of 10 subjects demonstrated satisfactory HAI titers (≥40) after seasonal influenza vaccination between 1 and 6 months post‐vaccine. These sera were then tested for inhibitory activity against A/HK/483/97 and A/Thailand/1(KAN‐1)/04 H5N1 influenza viruses using standard hemagglutination inhibition and microneutralization assays. In contrast to several other studies in both humans and animals on the cross‐immunity between different influenza A viruses, antibodies produced to the influenza A(H1N1) component of the seasonal influenza vaccine showed no cross‐reactivity to these avian influenza A(H5N1) viruses. Possible reasons for this contrasting result are discussed. J. Med. Virol. 80:1992–1996, 2008. © 2008 Wiley‐Liss, Inc.</div></front></TEI><affiliations><list><country><li>Hong Kong</li><li>République populaire de Chine</li></country><settlement><li>Sha Tin</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Tang, Julian W" sort="Tang, Julian W" uniqKey="Tang J" first="Julian W." last="Tang">Julian W. Tang</name></noRegion><name sortKey="Chan, Paul K S" sort="Chan, Paul K S" uniqKey="Chan P" first="Paul K. S." last="Chan">Paul K. S. Chan</name><name sortKey="Chan, Paul K S" sort="Chan, Paul K S" uniqKey="Chan P" first="Paul K. S." last="Chan">Paul K. S. Chan</name><name sortKey="Ngai, Karry L K" sort="Ngai, Karry L K" uniqKey="Ngai K" first="Karry L. K." last="Ngai">Karry L. K. Ngai</name></country><country name="Hong Kong"><noRegion><name sortKey="Chan, Paul K S" sort="Chan, Paul K S" uniqKey="Chan P" first="Paul K. S." last="Chan">Paul K. S. Chan</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001318 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001318 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:3AA3B59181D9E3A52D039146E92B16F2E0E94C9E
|texte= Lack of cross‐immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans
}}
| This area was generated with Dilib version V0.6.33. |  |